Anti-Collagenase Activity of Extract of Brokoli (Brassica oleocera L. var italica), Carrot (Daucus carota L.) and Chili pepper (Capsicum annuum L.)

  • Aisyah Fatmawaty Fakultas Farmasi, Universitas Hasanuddin
  • Angriani Angriani Fakultas Farmasi, Universitas Hasanuddin

Abstract

Collagenase is an enzyme family of Matrix Metalloproteinase (MMP) that breaks down collagen and degrade the extracellular matrix resulting in wrinkles and changes in skin thickness. This study was aimed to determine the value of inhibition concentration of flower extracts of broccoli (Brassica oleocera L. var Italica), carrot extract (Daucus Carota L.) and extract of chili pepper (Capsicum annuum L.) as collagenase inhibitor. Collagenase inhibitory activity was determined by measuring the product resulted from the reaction of enzyme and substrate using a microplate reader at λ 345 nm. Results showed that the inhibition of the flowers of broccoli, carrot and chili pepper ekstrak were 88.49%; 53.96% and 89.21% at a concentration of 250 ug / ml.

Published
Aug 26, 2019
How to Cite
FATMAWATY, Aisyah; ANGRIANI, Angriani. Anti-Collagenase Activity of Extract of Brokoli (Brassica oleocera L. var italica), Carrot (Daucus carota L.) and Chili pepper (Capsicum annuum L.). Journal of Pharmaceutical and Medicinal Sciences, [S.l.], v. 3, n. 2, aug. 2019. ISSN 2580-328X. Available at: <http://jpms-stifa.com/index.php/jpms/article/view/71>. Date accessed: 13 nov. 2019. doi: http://dx.doi.org/10.32814/jpms.v3i2.71.
Section
Articles