Activity, Formulation and Effectiveness of Liquid Soap Preparations of Arachis hypogaea L. Against Escherichia coli and Staphylococcus aureus

  • Sukriani Kursia Sekolah Tinggi Ilmu Farmasi Makassar
  • Aisyah Fatmawaty Fakultas Farmasi, Universitas Hasanuddin
  • Mutmainnah Hafid Sekolah Tinggi Ilmu Farmasi Makassar

Abstract

Utilization of Arachis hypogaea L. which has the potential as antibacterial. This is due to the presence of compounds that have the potential to be antibacterial, namely alkaloids, flavonoids, saponins, terpenoids and tannins. This study aims to determine the activity, formulation, and evaluation of preparations and to test the effectiveness of liquid soap preparations from ethanol extract of peanut outer shells against Escherichia coli and Staphylococcus aureus bacteria. Extraction was carried out by maceration method using 70% ethanol, testing for antibacterial activity using agar diffusion method and then formulated using surfactant variations and evaluating preparations including organoleptic, testing pH, specific gravity, viscosity, and foam height and testing the effectiveness of liquid soap. The results showed that the extract yield was 6.5%. The results of the One-Way ANOVA data analysis on the antibacterial activity test showed that there were differences between the various treatments with a value of p=0.000 (p>0.05). The evaluation results of soap show that the three formulas meet SNI standards. And for the results of the LSD analysis, the data on the effectiveness of liquid soap preparations showed that the value of p=0.334 means that Formula 1 and 2 are not significant (p>0.05) and formulas 2 and 3 are significant with p=0.042 (p<0.05). The effectiveness of liquid soap from the peanut outer shell waste extract was influenced by the surfactant concentration.

Published
Jan 3, 2021
How to Cite
KURSIA, Sukriani; FATMAWATY, Aisyah; HAFID, Mutmainnah. Activity, Formulation and Effectiveness of Liquid Soap Preparations of Arachis hypogaea L. Against Escherichia coli and Staphylococcus aureus. Journal of Pharmaceutical and Medicinal Sciences, [S.l.], v. 5, n. 2, jan. 2021. ISSN 2580-328X. Available at: <http://jpms-stifa.com/index.php/jpms/article/view/120>. Date accessed: 29 apr. 2024. doi: http://dx.doi.org/10.32814/jpms.v5i2.120.
Section
Articles